From Bucks County and points north
Southbound via I-95
Take Exit 22, following the signs for the Historic Area and Independence Hall. Go straight on 2nd Street to Walnut Street. Turn right onto Walnut and go one block to 3rd Street. Turn right onto 3rd Street and go one block to Chestnut Street. The Museum is on the right at 3rd and Chestnut Streets.
From Delaware and points south
Northbound via I-95
Take exit 22 for I-676/Independence Hall (left exit), keep right for I-676 east/Independence Hall to Callowhill Street, go straight on Callowhill Street to 4th Street. Turn left on 4th Street. Turn left on Chestnut Street, go one block and the Museum is on the right at 3rd and Chestnut Streets.